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Benhur Lee Selected Research

Henipavirus Infections

1/2018Favipiravir (T-705) protects against Nipah virus infection in the hamster model.
1/2016The Matrix Protein of Nipah Virus Targets the E3-Ubiquitin Ligase TRIM6 to Inhibit the IKKε Kinase-Mediated Type-I IFN Antiviral Response.
3/2015Timing of galectin-1 exposure differentially modulates Nipah virus entry and syncytium formation in endothelial cells.
6/2011Hendra and nipah infection: pathology, models and potential therapies.
3/2010Combined chloroquine and ribavirin treatment does not prevent death in a hamster model of Nipah and Hendra virus infection.
4/2007Envelope-receptor interactions in Nipah virus pathobiology.
7/2005EphrinB2 is the entry receptor for Nipah virus, an emergent deadly paramyxovirus.
7/2005Novel innate immune functions for galectin-1: galectin-1 inhibits cell fusion by Nipah virus envelope glycoproteins and augments dendritic cell secretion of proinflammatory cytokines.

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Benhur Lee Research Topics

Disease

30Infections
04/2022 - 03/2002
12COVID-19
04/2022 - 08/2020
10Virus Diseases (Viral Diseases)
04/2022 - 03/2002
8Henipavirus Infections
01/2018 - 07/2005
6Vesicular Stomatitis
05/2021 - 06/2011
4Human Influenza (Influenza)
01/2022 - 02/2010
4HIV Infections (HIV Infection)
10/2018 - 06/2002
2Severe Acute Respiratory Syndrome
01/2022 - 01/2021
2Persistent Infection
07/2013 - 03/2013
1Emerging Communicable Diseases (Emerging Infectious Diseases)
04/2022
1Wounds and Injuries (Trauma)
12/2021
1Viral Pneumonia
04/2021
1Paramyxoviridae Infections (Parainfluenza)
01/2020
1Bronchiolitis
01/2020
1Pneumonia (Pneumonitis)
01/2020
1Sudden Infant Death (SID)
11/2018
1Mumps
01/2017
1Carcinoma (Carcinomatosis)
01/2017
1Herpes Simplex
10/2016
1Lymphedema (Milroy Disease)
09/2015
1Carcinogenesis
02/2013
1Neoplasms (Cancer)
02/2013
1Multiple Myeloma
11/2010
1Anthrax
07/2006
1Parasitic Diseases (Parasitic Disease)
07/2005

Drug/Important Bio-Agent (IBA)

10Proteins (Proteins, Gene)FDA Link
01/2022 - 07/2005
9Glycoproteins (Glycoprotein)IBA
01/2021 - 07/2005
8VaccinesIBA
01/2022 - 03/2010
7AntibodiesIBA
02/2022 - 01/2017
6Antiviral Agents (Antivirals)IBA
04/2022 - 02/2010
5Neutralizing AntibodiesIBA
01/2022 - 01/2017
4Pharmaceutical PreparationsIBA
01/2018 - 03/2010
4DC-specific ICAM-3 grabbing nonintegrin (DC-SIGN)IBA
08/2007 - 03/2002
3Immunoglobulin A (IgA)IBA
01/2022 - 12/2020
3CytokinesIBA
12/2021 - 07/2005
3Monoclonal AntibodiesIBA
01/2021 - 12/2009
3Immunoglobulin G (IgG)IBA
01/2021 - 12/2020
3Immunoglobulin M (IgM)IBA
01/2021 - 12/2020
3Galectin 1 (LGALS1)IBA
09/2015 - 07/2005
3Polysaccharides (Glycans)IBA
03/2015 - 07/2005
3LectinsIBA
03/2015 - 06/2002
2Immunoglobulin IsotypesIBA
01/2021 - 12/2020
2Immunoglobulins (Immunoglobulin)IBA
01/2021 - 12/2020
2LipidsIBA
01/2016 - 04/2013
2Galectins (Galectin)IBA
03/2015 - 07/2010
2Ribavirin (Virazole)FDA LinkGeneric
06/2011 - 03/2010
2LigandsIBA
07/2010 - 12/2009
2C-Type Lectins (C-Type Lectin)IBA
08/2007 - 03/2002
1Interferon Type IIBA
04/2022
1PalmitatesIBA
04/2022
1InterferonsIBA
04/2022
1RNA (Ribonucleic Acid)IBA
01/2022
1ImmunosorbentsIBA
01/2022
1RNA Helicases (RNA Helicase)IBA
01/2022
1Secretory Immunoglobulin A (SIgA)IBA
01/2022
1mRNA VaccinesIBA
01/2022
1EnzymesIBA
01/2022
1Peptide Hydrolases (Proteases)FDA Link
12/2021
1MicroRNAs (MicroRNA)IBA
12/2021
1Viral ProteasesIBA
12/2021
1PolyproteinsIBA
12/2021
1NucleoproteinsIBA
12/2021
1PapainIBA
12/2021
1RibonucleoproteinsIBA
12/2021
1Viral RNAIBA
12/2021
1FurinIBA
01/2021
1Renilla LuciferasesIBA
01/2021
1NucleosidesIBA
10/2020
1Viral ProteinsIBA
01/2020
1Codon (Codons)IBA
11/2018
1SAM Domain and HD Domain-Containing Protein 1IBA
10/2018
1Interleukin-15 (Interleukin 15)IBA
10/2018
1ruxolitinibIBA
10/2018
1purineIBA
01/2018
1favipiravirIBA
01/2018
1erucylphosphocholineIBA
01/2017
1Phospholipids (Phosphatides)FDA LinkGeneric
01/2017
1CD4 Antigens (CD4 Antigen)IBA
01/2017
1Lipid Bilayers (Lipid Bilayer)IBA
01/2017
1Singlet OxygenIBA
01/2017
1Podophyllotoxin (Condylox)FDA LinkGeneric
10/2016
1Viral DNAIBA
01/2016
1saccharide-binding proteinsIBA
03/2015
1Pattern Recognition ReceptorsIBA
03/2015
1recombinant soluble CD4IBA
07/2013
1IntegrinsIBA
06/2011
1LuciferasesIBA
06/2011
1Complement System Proteins (Complement)IBA
06/2011
1Proteasome InhibitorsIBA
11/2010
1Bortezomib (Velcade)FDA Link
11/2010
1Membrane Glycoproteins (Membrane Glycoprotein)IBA
07/2010
1Chloroquine (Aralen)FDA LinkGeneric
03/2010
1Antimalarials (Antimalarial Agents)IBA
03/2010
1Mannose (D-Mannose)IBA
08/2007
1anthrax toxin receptorsIBA
07/2006
1Interleukin-6 (Interleukin 6)IBA
07/2005
11-nitrohydroxyphenyl-N-benzoylalanine (GAL 1)IBA
07/2005
1Member 1 Subfamily B ATP Binding Cassette TransporterIBA
03/2005

Therapy/Procedure

8Therapeutics
01/2021 - 07/2005
1Art Therapy
01/2013